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The Sub-lethal and Transgenerational Effects of Fluoxetine and Sertraline on Daphnia magna

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Title: The Sub-lethal and Transgenerational Effects of Fluoxetine and Sertraline on Daphnia magna
Author: Halliwushka, Kelsey
Department: Department of Integrative Biology
Program: Integrative Biology
Advisor: Heyland, Andreas
Abstract: With pharmaceutical use on the rise, there is a growing concern over the release of pharmaceuticals into the aquatic environment. The purpose of the present study was to determine the lethal and sub-lethal effects of two pharmaceuticals - fluoxetine and sertraline - on the life history traits of Daphnia magna. While environmentally relevant concentrations did not increase mortality in D. magna, acute exposures did alter heart rate, swimming ability, and reproductive output. Acute exposures had lasting transgenerational effects on swimming and reproductive output. However, no transgenerational effects on heart rate were found. These findings indicate that the current levels of fluoxetine and sertraline found in the environment are causing lasting effects on D. magna. Because of the short reproductive period of daphnia and their integral role in the food web, these lasting effects may have population-level implications in a rapid period of time.
URI: http://hdl.handle.net/10214/9930
Date: 2016-09
Rights: Attribution 2.5 Canada


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Attribution 2.5 Canada Except where otherwise noted, this item's license is described as Attribution 2.5 Canada