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The Effect of Resistant Starch Bagels on Glycemic Response in Adults at Risk for Type 2 Diabetes

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dc.contributor.advisor Duncan, Alison M. Dainty, Sarah A. 2015-05-04T14:42:53Z 2015-05-04T14:42:53Z 2015-05 2015-04-28 2015-05-04
dc.description A human clinical trial to determine the effect of resistant starch bagels on glycemic response in adults at risk for type 2 diabetes en_US
dc.description.abstract Acute and chronic resistant starch (RS) consumption has been shown to improve glycemia, however, more chronic interventions using high-RS foods are needed in individuals at increased risk of type 2 diabetes (T2D). A randomized, double-blind crossover study was conducted to examine the glycemic effects of 8-week consumption of high-RS bagels (25 g RS) or control bagels in high-T2D risk adults (n=24). Fasting and postprandial (with an oral glucose tolerance test) glucose, insulin and HbA1c were measured before and after each bagel treatment. Compared to the control bagel, the RS bagel did not change fasting or postprandial glucose or HbA1c but significantly reduced fasting insulin, 2- and 3-hour insulin iAUC, fasting insulin resistance (HOMA-IR) and beta-cell function (HOMA-%B), and significantly increased fasting insulin sensitivity (HOMA-%S). These results demonstrated that high-RS bagel consumption improves fasting and postprandial insulin sensitivity and provide evidence for a feasible dietary strategy to reduce T2D risk. en_US
dc.description.sponsorship Canada Bread Limited and Ontario Ministry of Agriculture, Food and Rural Affairs en_US
dc.language.iso en en_US
dc.subject resistant starch en_US
dc.subject type 2 diabetes en_US
dc.subject glycemic response en_US
dc.subject randomized crossover trial en_US
dc.subject insulin sensitivity en_US
dc.subject insulin resistance en_US
dc.subject HbA1c en_US
dc.subject fasting glucose en_US
dc.subject fasting insulin en_US
dc.subject postprandial glycemic response en_US
dc.subject bagels en_US
dc.title The Effect of Resistant Starch Bagels on Glycemic Response in Adults at Risk for Type 2 Diabetes en_US
dc.type Thesis en_US Human Health and Nutritional Sciences en_US Master of Science en_US Department of Human Health and Nutritional Sciences en_US
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