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Informing Giardia surveillance and giardiasis prevention in a FoodNet Canada sentinel site through an investigation of local surface waters and risk factors associated with domestic and foreign travel

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dc.contributor.advisor Pearl, David
dc.contributor.author Swirski, Alexandra
dc.date.accessioned 2015-01-08T15:15:22Z
dc.date.available 2015-01-08T15:15:22Z
dc.date.copyright 2014-12
dc.date.created 2014-12-19
dc.date.issued 2015-01-08
dc.identifier.uri http://hdl.handle.net/10214/8683
dc.description.abstract Two studies were conducted to explore source attribution of human giardiasis cases in the Region of Waterloo, Ontario by examining local watershed contamination with Giardia cysts and identifying differences in exposures to risk factors in cases with travel history compared to endemic cases. Linear regression models were constructed to identify temporal trends in water contamination with Giardia, as well as water quality parameters that may indicate high cyst levels. Logistic regression models were constructed to determine if there were significant differences in risk behaviours among international travel related giardiasis cases compared to Canadian acquired cases. Multinomial regression models were then constructed to determine significant differences in risk behaviours between international travel related cases, domestic travel related cases, and endemic cases of giardiasis. Giardia cyst concentrations peak in the winter and spring months in the Grand River and river discharge, turbidity, conductivity, phosphate concentration and phosphorous concentration were significantly associated with Giardia cyst concentrations. Results from both logistic and multinomial regression models indicated that risk behaviours differ significantly between case types and the traditional grouping of domestic travel related cases and endemic cases into a Canadian acquired case group may not be appropriate. These results are important for future Giardia surveillance, source attribution, informing policy makers, and effectively targeting health promotion campaigns for reducing human giardiasis in this region. en_US
dc.language.iso en en_US
dc.subject Giardia en_US
dc.subject giardiasis en_US
dc.subject surveillance en_US
dc.subject travel en_US
dc.subject water en_US
dc.subject FoodNet en_US
dc.title Informing Giardia surveillance and giardiasis prevention in a FoodNet Canada sentinel site through an investigation of local surface waters and risk factors associated with domestic and foreign travel en_US
dc.type Thesis en_US
dc.degree.programme Population Medicine en_US
dc.degree.name Master of Science en_US
dc.degree.department Department of Population Medicine en_US


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