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Dietary Vitamin D Intake and Vitamin D Status in Canine Cancer Patients

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dc.contributor.advisor Verbrugghe, Adronie Weidner, Nicole 2015-01-06T20:06:04Z 2015-12-19T06:00:11Z 2014-12 2014-12-19 2015-01-06
dc.description.abstract In humans, low dietary vitamin D intake and a low vitamin D status have been linked to increased risk of cancer development. This association is starting to be explored in canines. This thesis is an investigation of the dietary vitamin D intake and vitamin D status of dogs with cancer, specifically osteosarcoma, lymphoma and mast cell tumours, in comparison to healthy dogs. Plasma 25(OH)D concentration was significantly higher in healthy dogs than in those with osteosarcoma and lymphoma, but not mast cell tumours. There was an independent effect of cancer, dietary vitamin D intake and plasma ionized calcium on plasma 25(OH)D concentrations. The independent effect of cancer suggests that dietary vitamin D intake is not responsible for observed differences in plasma 25(OH)D concentrations. Further research is needed to investigate whether decreased plasma 25(OH)D concentrations are a factor in cancer development, or a consequence of cancer. en_US
dc.description.sponsorship OVC Pet Trust, AAVN/Waltham Research Grant, Royal Canin en_US
dc.language.iso en en_US
dc.subject Vitamin D en_US
dc.subject Lymphoma en_US
dc.subject Osteosarcoma en_US
dc.subject Mast cell tumour en_US
dc.subject Dog en_US
dc.subject Canine en_US
dc.subject Canine cancer en_US
dc.subject Cancer en_US
dc.subject Vitamin D intake en_US
dc.subject Vitamin D status en_US
dc.subject 25(OH)D en_US
dc.title Dietary Vitamin D Intake and Vitamin D Status in Canine Cancer Patients en_US
dc.type Thesis en_US Clinical Studies en_US Master of Science en_US Department of Clinical Studies en_US

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