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Investigation into Factors Associated with Surgical Site Infections Following Tibial Plateau Leveling Osteotomy in Dogs

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dc.contributor.advisor Singh, Ameet
dc.contributor.author Nazarali, Alim
dc.date.accessioned 2014-09-03T18:08:55Z
dc.date.available 2014-09-03T18:08:55Z
dc.date.copyright 2014-08
dc.date.created 2014-08-26
dc.date.issued 2014-09-03
dc.identifier.uri http://hdl.handle.net/10214/8395
dc.description.abstract Tibial plateau leveling osteotomy (TPLO) is one of the most common surgical techniques performed to stabilize a cranial cruciate insufficient stifle in dogs. Although it is classified as a clean surgical procedure, it is associated with a high surgical site infection (SSI) rate. Methicillin-resistant Staphylococcus pseudintermedius (MRSP) is the predominant pathogen causing TPLO SSI and is difficult to treat because of its multi-drug resistance. This thesis is an investigation into the use of perioperative antimicrobial prophylaxis and factors associated with SSI occurrence following TPLO in dogs, including MRSP carriage. We identified that perioperative antimicrobial prophylaxis protocols are not being administered appropriately, however, failure of adherence to these protocols was not associated with SSI. Furthermore, preoperative MRSP carriage was a risk factor and postoperative antimicrobial use was protective against the occurrence of TPLO SSI. Further study into the factors associated with TPLO SSI is required to understand this clinically important challenge. en_US
dc.description.sponsorship OVC Pet Trust Fund en_US
dc.language.iso en en_US
dc.subject TPLO en_US
dc.subject SSI en_US
dc.subject Antimicrobial Prophylaxis en_US
dc.subject MRSP en_US
dc.subject MRSP carriage en_US
dc.title Investigation into Factors Associated with Surgical Site Infections Following Tibial Plateau Leveling Osteotomy in Dogs en_US
dc.type Thesis en_US
dc.degree.programme Clinical Studies en_US
dc.degree.name Master of Science en_US
dc.degree.department Department of Clinical Studies en_US


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