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Characterization of Efficacy and Release Patterns in a Slow-Release Formulation of Novaluron

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Title: Characterization of Efficacy and Release Patterns in a Slow-Release Formulation of Novaluron
Author: McManus, Padraeg
Department: School of Environmental Sciences
Program: Environmental Sciences
Advisor: Hall, J. Christopher
Abstract: Mosquitoes are vectors of human disease such as malaria and it is important to control mosquito populations at breeding sites such as standing water. Many pesticides including novaluron, a benzoylphenyl urea, are effective at controlling mosquitoes; however, reapplication may be required to provide continued control. A slow-release, wax-based formulation of novaluron was developed to regulate the release of novaluron in standing water to prolong mosquito control. Under laboratory conditions, concentrations of novaluron from this formulation along with another formulation were quantified in water with different chemical and/or physical properties for 6 months. The study determined that the formulations released novaluron consistently regardless of water condition. Subsequently, the wax-based formulation was added to aquatic mesocosms to measure efficacy over four months against target (mosquito larvae) and non-target (zooplankton) species under natural conditions. Emergence of adult Aedes aegypti was inhibited for 121 days; though zooplankton populations were reduced. Data from this research was contributed to a positive registration decision for these formulations in Canada and the United States.
Date: 2013-12
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