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Design and validation of a cadaveric knee joint loading device compatible with magnetic resonance imaging and micro computed tomography

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dc.contributor.advisor Gordon, Karen
dc.contributor.author Chen, Larry
dc.date.accessioned 2014-01-07T17:56:03Z
dc.date.available 2014-01-07T17:56:03Z
dc.date.copyright 2013-12
dc.date.created 2013-12-18
dc.date.issued 2014-01-07
dc.identifier.uri http://hdl.handle.net/10214/7769
dc.description.abstract Purpose: Design and validation of a magnetic resonance and computed tomography compatible device capable of applying muscle forces to cadaveric knee joints with high precision. Methods: Load was applied to two porcine knee joints at full extension, five and fifteen degrees of flexion. Five repeatability and five reproducibility trials were performed at each flexion angle. Standard deviations (SDs) of joint angle and load were reported. Results: For repeatability, the maximum SDs for joint angle were 1.26° (flexion), 1.54° (ab/adduction) and 0.90° (in/external rotation). The maximum SDs for joint load were 4.60N (anterior/posterior), 7.36N (medial/lateral), and 42.6N (axial). For reproducibility, the maximum SDs for joint angle were 0.84° (flexion), 0.66° (ab/adduction) and 0.92° (in/external rotation). The maximum SDs for joint load were 6.40N (anterior/posterior), 11.7N (medial/lateral), and 39.7N (axial). Conclusions: This level of repeatability/reproducibility is within intra-subject gait variance. Therefore, this device can be an effective tool for in-vitro testing. en_US
dc.description.sponsorship This study was funded by the National Science and Engineering Research Council and the Canadian Institutes for Health Research (QNT 68722). en_US
dc.language.iso en en_US
dc.subject orthopaedic biomechanics en_US
dc.subject medical imaging en_US
dc.subject in-vitro knee en_US
dc.title Design and validation of a cadaveric knee joint loading device compatible with magnetic resonance imaging and micro computed tomography en_US
dc.type Thesis en_US
dc.degree.programme Engineering en_US
dc.degree.name Master of Applied Science en_US
dc.degree.department School of Engineering en_US


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