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Following exercise, complex chemical signals control the activity of energy-producing mitochondria in muscle cells

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Title: Following exercise, complex chemical signals control the activity of energy-producing mitochondria in muscle cells
Author: Frier, B.C.; Hancock, C.R.; Little, J.P.; et al; Institute for Community Engaged Scholarship
Abstract: Exercise, or injection with the chemical signals released following exercise, increased the production of mitochondrial proteins in muscle cells. Increased levels of the activating protein PGC-1α alone were able to bring about the increase in mitochondrial activity, even when levels of the inhibiting protein RIP140 remained high. This means that the production of mitochondria in skeletal muscle following exercise is not controlled by a reduction in RIP140, as was previously thought.
Description: This summary is a project of the Institute for Community Engaged Scholarship (ICES) at the University of Guelph, with project partners: the Business Development Office (BDO), SPARK Program at the University of Guelph, and Knowledge Mobilization Unit at York University. This project is part of the Pan-Canadian Research Impact Network. http://csahs.uoguelph.ca/pps/Clear_Research
URI: http://hdl.handle.net/10214/5493
Date: 2013-02-08
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