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Cannabidiol, a non-intoxicating component of cannabis, suppresses nausea and vomiting in rats and shrews

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Title: Cannabidiol, a non-intoxicating component of cannabis, suppresses nausea and vomiting in rats and shrews
Author: Rock, E.M.; Bolognini, D.; Limebeer, C.L.; Cascio, M.G.; Anavi-Goffer, S.; Fletcher, P.J.; Mechoulam, R.; Pertwee, R.G.; Parker, L.A.; Institute for Community Engaged Scholarship
Abstract: Cannabidiol suppressed drug-induced vomiting in shrews and nausea-associated behaviours in rats. This effect was reversed, however, if the rodents were also given chemicals that blocked serotonin receptors in a part of the brainstem. Cannabidiol may help naturally produced serotonin activate these receptors more effectively.
Description: This summary is a project of the Institute for Community Engaged Scholarship (ICES) at the University of Guelph, with project partners: the Catalyst Centre, SPARK Program at the University of Guelph, and Knowledge Mobilization Unit at York University. This project is part of the Pan-Canadian Research Impact Network. http://csahs.uoguelph.ca/pps/Clear_Research
URI: http://hdl.handle.net/10214/5491
Date: 2013-02-08


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