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Efficacy of a yeast cell wall-derived mycotoxin adsorbent on excretion of aflatoxin B2 in weanling rats

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dc.contributor.advisor Smith, Trevor
dc.contributor.author Walters, Brandon
dc.date.accessioned 2013-01-03T17:51:57Z
dc.date.available 2013-01-03T17:51:57Z
dc.date.copyright 2012-12
dc.date.created 2012-12-17
dc.date.issued 2013-01-03
dc.identifier.uri http://hdl.handle.net/10214/5199
dc.description.abstract Mycotoxins are natural contaminants of livestock feeds that can impair production efficiency. Specialized feed additives known as mycotoxin adsorbents may reduce absorption of mycotoxins in animals. Many additives are thought to use nonspecific binding to sequester mycotoxins in the lumen of the gastrointestinal tract, but there is a lack of in vivo mechanistic evidence. The current research sought to quantify the adsorptive capabilities of a yeast cell wall-derived mycotoxin adsorbent and confirm whether its mode of action is by adsorption of the mycotoxin. Using radioactive aflatoxin B2, it was found that there was a significant reduction in urine radioactivity when the adsorbent was present and observed over time. No other significant effects of diet were noticed in the liver, kidneys or muscle. Without feces and tissue data in agreement with urine, it was inconclusive whether this adsorbent reduced absorption of aflatoxin in rats. en_US
dc.description.sponsorship OMAFRA, Alltech en_US
dc.language.iso en en_US
dc.title Efficacy of a yeast cell wall-derived mycotoxin adsorbent on excretion of aflatoxin B2 in weanling rats en_US
dc.type Thesis en_US
dc.degree.programme Animal and Poultry Science en_US
dc.degree.name Master of Science en_US
dc.degree.department Department of Animal and Poultry Science en_US
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