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The Ontogeny of Blood Oxygen Transport and the Hypoxia Response in Early Life Stages of the Rainbow Trout, Oncorhynchus mykiss

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dc.contributor.advisor Wright, Pat
dc.contributor.author Bianchini, Kristin
dc.date.accessioned 2012-11-13T14:45:20Z
dc.date.available 2012-11-13T14:45:20Z
dc.date.copyright 2012-10
dc.date.created 2012-10-30
dc.date.issued 2012-11-13
dc.identifier.uri http://hdl.handle.net/10214/4323
dc.description.abstract In early rainbow trout development, a switch from high-affinity embryonic hemoglobin to lower-affinity adult hemoglobin occurs along with a turnover of round, embryonic erythrocytes to oval, adult erythrocytes. The objective of my thesis was to determine how the ontogeny of blood oxygen transport was affected by chronic hypoxia (30% of saturation) in rainbow trout. Hemoglobin-oxygen affinity, cooperativity, and the Bohr and Root effects were unaffected by hypoxia treatments, whereas hemoglobin content, erythrocyte counts, and hematocrit were significantly reduced. In hypoxia, larvae had higher concentrations of embryonic hemoglobin mRNA and embryonic erythrocytes than stage-matched normoxia-reared larvae. Overall, these results indicate that chronic hypoxia suppresses erythrocyte development prior to complete yolk absorption. Ultimately, this suggests that in early ontogeny rainbow trout conform to low oxygen conditions, rather than mounting the hypoxia response observed in oxygen-regulating adult trout. en_US
dc.language.iso en en_US
dc.rights.uri http://creativecommons.org/licenses/by-nc-nd/2.5/ca/ *
dc.subject Hypoxia en_US
dc.subject Developmental biology en_US
dc.subject Hemoglobin en_US
dc.subject Blood en_US
dc.subject Rainbow trout en_US
dc.title The Ontogeny of Blood Oxygen Transport and the Hypoxia Response in Early Life Stages of the Rainbow Trout, Oncorhynchus mykiss en_US
dc.type Thesis en_US
dc.degree.programme Integrative Biology en_US
dc.degree.name Master of Science en_US
dc.degree.department Department of Integrative Biology en_US


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http://creativecommons.org/licenses/by-nc-nd/2.5/ca/ Except where otherwise noted, this item's license is described as http://creativecommons.org/licenses/by-nc-nd/2.5/ca/