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Soy consumption, but not dairy consumption, is inversely associated with fatty acid desaturase activity in young adults

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dc.contributor.advisor Mutch, David Gonzalez Soto, Melissa 2021-08-27T14:31:03Z 2021-08-27T14:31:03Z 2021-08 2021-08-03 2021-08-17
dc.description.abstract Past evidence in animals showed that soy protein consumption suppressed delta-6 desaturase (D6D) activity compared to casein, however the effects of soy protein consumption on fatty acid desaturation remains poorly explored in humans. This thesis investigated the association between the consumption of soy and dairy beverages and foods with plasma fatty acid levels and estimated desaturase pathway activity in a multiethnic Canadian population of young adults. Food frequency data and plasma fatty acid data previously collected for the Toronto Nutrigenomics and Health Study were analyzed. Significant inverse associations (p≤0.05) were found between soy consumption and overall desaturation pathway activity. Plasma levels of omega-6 long-chain PUFAs, as well as various estimates of desaturase pathway activity, were significantly lower in individuals consuming soy compared to individuals consuming only fluid milk and dairy products. Collectively, these findings suggest that soy consumption, but not dairy intake, is inversely associated with desaturase pathway activity. en_US
dc.description.sponsorship Consejo Nacional de Ciencia y Tecnología (CONACyT) en_US
dc.language.iso en en_US
dc.publisher University of Guelph en_US
dc.subject humans en_US
dc.subject fluid milk en_US
dc.subject dairy en_US
dc.subject soy beverage en_US
dc.subject plant-based beverage en_US
dc.subject LC-PUFA en_US
dc.subject delta-6 desaturase en_US
dc.subject omega-3 en_US
dc.subject omega-6 en_US
dc.title Soy consumption, but not dairy consumption, is inversely associated with fatty acid desaturase activity in young adults en_US
dc.type Thesis en_US Human Health and Nutritional Sciences en_US Master of Science en_US Department of Human Health and Nutritional Sciences en_US
dc.rights.license All items in the Atrium are protected by copyright with all rights reserved unless otherwise indicated.
dcterms.relation Gonzalez-Soto M, Abdelmagid SA, Ma DWL, El-Sohemy A, Mutch DM. Soy Consumption, but Not Dairy Consumption, Is Inversely Associated with Fatty Acid Desaturase Activity in Young Adults. Nutrients 2021;13(8):2817. en_US University of Guelph en_US

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