Main content

Particle Tracking and Lock-in Detection for Microfluidic Systems

Show full item record

Title: Particle Tracking and Lock-in Detection for Microfluidic Systems
Author: Devasagayam, Jasen
Department: School of Engineering
Program: Engineering
Advisor: Collier, Christopher
Abstract: Milk intended for human consumption is strictly regulated for antibiotics, to prevent health problems, including allergic reactions and antibacterial resistance. Currently, testing is performed on bulk milk tanks, where, if contaminated, an entire tank is discarded. Microfluidic devices could provide on-farm testing, however, current microfluidic methods do not achieve the regulated antibiotics limit. This thesis presents developments in microfluidics towards this goal. A microparticle tracking velocimetry MATLAB program is developed and compared to mathematical models. This is tested for pressure-driven and electrophoresis applications. Moreover, microchip capillary electrophoresis is further explored with lock-in amplification to reduce system noise when detecting antibiotics in milk samples. This integration provides a significant noise reduction. This work provides a foundation to develop rapid and reliable antibiotic detection systems in the dairy industry.
URI: https://hdl.handle.net/10214/25658
Date: 2021-04
Rights: Attribution-NonCommercial-NoDerivatives 4.0 International
Terms of Use: All items in the Atrium are protected by copyright with all rights reserved unless otherwise indicated.


Files in this item

Files Size Format View Description
Devasagayam_Jasen_202104_MASc.pdf 5.349Mb PDF View/Open MASc Thesis

This item appears in the following Collection(s)

Show full item record

Attribution-NonCommercial-NoDerivatives 4.0 International Except where otherwise noted, this item's license is described as Attribution-NonCommercial-NoDerivatives 4.0 International