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Identifying Hepatic Genes Regulating the Ovine Response to Gastrointestinal Nematodes

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Title: Identifying Hepatic Genes Regulating the Ovine Response to Gastrointestinal Nematodes
Author: Dixon, Samantha
Department: Department of Animal Biosciences
Program: Animal and Poultry Science
Advisor: Cánovas, AngelaKarrow, Niel
Abstract: Gastrointestinal nematode (GIN) infections are considered the most important disease of grazing sheep. Due to increasing anthelmintic resistance, chemical control alone is inadequate. Resistance to GINs is a heritable trait, and many breeds of sheep throughout the world have naturally developed enhanced resistance. The study of the transcriptome from GIN-exposed and unexposed sheep using RNA-Sequencing technology can provide measurements of transcript levels associated with the host response to the infection. The objective of this study was to examine liver transcriptome from high and medium stress responding tracer sheep (naturally GIN-exposed) and control sheep (unexposed) in order to identify key regulator genes and biological processes associated with GIN infection.
URI: http://hdl.handle.net/10214/16950
Date: 2019-07-29
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