Main content

Coexistence between Plasmids in Structured Bioflms: A Theoretical Model for Post-Segregational Killing Systems

Show full item record

Title: Coexistence between Plasmids in Structured Bioflms: A Theoretical Model for Post-Segregational Killing Systems
Author: Verweij, Wilco
Department: Department of Integrative Biology
Program: Integrative Biology
Advisor: Griswold, Cortland
Abstract: Currently there is a lack of understanding about how plasmids that contain Post-Segregational Killing (PSK+) systems and plasmids that do not contain such a system coexist in a population. In this thesis two spatially explicate models are presented to attempt to answer this gap in the literature. The rst model is an extension on a previous single strain model, the second model has two di erent strains and allows for the plasmids to specialize to di erent bacterial strains. Weak coexistence was found in the single strain model. Coexistence was found in the second model but only across a small parameter space and only under conditions when a PSK+ plasmid is introduce by a process analogous to dispersal. The interesting implication of this result is that it suggests coexistence is possible with specialization, but that it requires dispersal from another locality for the coexistence process to be initiated.
URI: http://hdl.handle.net/10214/16264
Date: 2019-06


Files in this item

Files Size Format View
Verweij_Wilco_201906_Msc.pdf 1.062Mb PDF View/Open

This item appears in the following Collection(s)

Show full item record