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IDENTIFICATION OF GENETIC MARKERS FOR STRESS RESPONSIVENESS AND MEAT QUALITY IN CANADIAN YORKSHIRE PIGS

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dc.contributor.advisor Lu, Ray
dc.contributor.author Larson, Shayla
dc.date.accessioned 2019-05-16T17:21:17Z
dc.date.available 2019-05-16T17:21:17Z
dc.date.copyright 2019
dc.date.created 2019-04-09
dc.date.issued 2019-05-16
dc.identifier.uri http://hdl.handle.net/10214/16129
dc.description.abstract Luman/CREB3 is a stress gene that has recently been identified in mouse models and therefore presents a promising avenue for exploring the genetic component underlying stress-responsiveness in pigs. This thesis provides a detailed account of the genetic variation that exists naturally at the Luman gene of Canadian Yorkshire and Chinese Meishan breeding pigs. We present evidence that genetic variation in the swine Luman gene is associated with individual differences in behavioural coping styles for stress, physiological stress levels, and meat quality characteristics among pigs. Notably, two haplotypes (A1 and A2) were associated with lower activity levels and exploratory behaviours in response to novelty and human interaction as well as greater meat quality, whereas haplotypes B1 and B2 were associated with the opposite characteristics. We postulate that genetic variations in the swine Luman gene may be used as markers for robustness and meat quality in pigs for animal breeding purposes. en_US
dc.description.sponsorship Participating organizations and funding sources for this project include AGC (Alliance Genetics Canada), OMAFRA, NSERC, CFREF, Swine Innovation Porc, and CCSI (Canadian Centre for Swine Improvement). en_US
dc.language.iso en en_US
dc.subject genetic marker en_US
dc.subject stress en_US
dc.subject meat quality en_US
dc.subject pigs en_US
dc.subject SNP en_US
dc.subject Luman en_US
dc.subject CREB3 en_US
dc.subject haplotype en_US
dc.subject Yorkshire en_US
dc.subject Meishan en_US
dc.subject genetic variation en_US
dc.title IDENTIFICATION OF GENETIC MARKERS FOR STRESS RESPONSIVENESS AND MEAT QUALITY IN CANADIAN YORKSHIRE PIGS en_US
dc.type Thesis en_US
dc.degree.programme Molecular and Cellular Biology en_US
dc.degree.name Master of Science en_US
dc.degree.department Department of Molecular and Cellular Biology en_US
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