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The Epidemiology of Borrelia burgdorferi in Horses in Ontario and Assessment of Serologic Testing Methods

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Title: The Epidemiology of Borrelia burgdorferi in Horses in Ontario and Assessment of Serologic Testing Methods
Author: Neely, Megan
Department: Department of Pathobiology
Program: Pathobiology
Advisor: Weese, J. Scott
Abstract: The objectives of this thesis were to determine the seroprevalence of Borrelia burgdorferi and Anaplasma phagocytophilum antibodies in horses in Ontario, identify demographic and management factors associated with B. burgdorferi seropositivity and compare the ability of a point-of-care ELISA to a Multiplex ELISA to detect B. burgdorferi antibodies over time. Serum samples from 551 horses from 76 veterinary clinics were submitted along with 473 accompanying questionnaires filled out by the owners of the horses. The overall prevalence of B. burgdorferi seropositivity for horses on at least one test was 17% (91/551). The odds of being seropositive were increased by the presence of oak trees near the horses’ pastures. A high-risk cluster was also identified in Eastern Ontario. Performing regular checks for ticks was associated with decreased odds of seropositivity. Agreement between the two ELISA tests was fair (kappa=0.23) and horses remained seropositive one year after initial testing on both tests.
URI: http://hdl.handle.net/10214/16077
Date: 2019-05


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