Main content

The Long-Term Effects of Environmental Enrichment on Agonism in Female C57BL/6, DBA/2, and BALB/c Mice

Show simple item record

dc.contributor.advisor Mason, Georgia
dc.contributor.author Nip, Emma
dc.date.accessioned 2018-09-13T15:42:12Z
dc.date.available 2018-09-13T15:42:12Z
dc.date.copyright 2018-09
dc.date.created 2018-09-06
dc.date.issued 2018-09-13
dc.identifier.uri http://hdl.handle.net/10214/14288
dc.description.abstract Female mice are usually kept in non-enriched shoebox cages that increase agonism. I sought to understand why environmental enrichment (EE) reduces agonism by observing home-cage agonism, stereotypic behaviour, and inactive-but-awake behaviour (IBA: a depressive-like state), and by assessing hearing loss and anxiety, in 165 mice (C57BL/6s, BALB/cs, and DBA/2s). I employed statistics to see if any of these variables predicted agonism; only IBA did in some sub-groups. Low agonism in EE mice was also partially explained by low social interaction rates. Lastly, I assessed agonism in an unfamiliar arena with stranger mice, but enriched mice did not exhibit less agonism in this setting. Overall, these findings demonstrate that a) EE reduces agonism in females, b) IBA co-varies with agonism, c) low agonism is partially a by-product of low interaction rates, and d) enriched mice are no less agonistic than non-enriched mice when in an unfamiliar arena with strangers. en_US
dc.description.sponsorship GEES and OGS scholarships en_US
dc.language.iso en en_US
dc.publisher University of Guelph en_US
dc.subject Enrichment en_US
dc.subject Environmental Enrichment en_US
dc.subject Mice en_US
dc.subject Female en_US
dc.subject Aggression en_US
dc.subject Agonism en_US
dc.subject DBA/2 en_US
dc.subject C57BL/6 en_US
dc.subject BALB/c en_US
dc.title The Long-Term Effects of Environmental Enrichment on Agonism in Female C57BL/6, DBA/2, and BALB/c Mice en_US
dc.type Thesis en_US
dc.degree.programme Animal and Poultry Science en_US
dc.degree.name Master of Science en_US
dc.degree.department Department of Animal Biosciences en_US
dc.rights.license All items in the Atrium are protected by copyright with all rights reserved unless otherwise indicated.
dc.degree.grantor University of Guelph en_US


Files in this item

Files Size Format View Description
Nip_Emma_201809_MSc.pdf 1.748Mb PDF View/Open Revised version of thesis

This item appears in the following Collection(s)

Show simple item record

The library is committed to ensuring that members of our user community with disabilities have equal access to our services and resources and that their dignity and independence is always respected. If you encounter a barrier and/or need an alternate format, please fill out our Library Print and Multimedia Alternate-Format Request Form. Contact us if you’d like to provide feedback: lib.a11y@uoguelph.ca  (email address)