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THE EFFECTS OF A NUCLEOTIDE RICH YEAST SUPPLEMENT ON GROWTH PERFORMANCE, GASTROINTESTINAL ECOLOGY AND IMMUNE SYSTEM IN BROILER CHICKENS CHALLENGED WITH EIMERIA

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dc.contributor.advisor Kiarie, Elijah
dc.contributor.author Leung, Haley
dc.date.accessioned 2018-08-31T20:17:39Z
dc.date.available 2018-08-31T20:17:39Z
dc.date.copyright 2018-07
dc.date.created 2018-07-18
dc.date.issued 2018-08-31
dc.identifier.uri http://hdl.handle.net/10214/14157
dc.description.abstract Increased antibiotic free production has increased emphasis on poultry gut health leading to evaluation of dietary alternatives such as nucleotides to improve production. Therefore, yeast derived nucleotides were evaluated for effects on growth performance, gastrointestinal ecology and immune system short- (trial 1) and long-term (trial 2) experiments. Nucleotides improved growth performance in trial 1 but not in trial 2. Nucleotides improved cationic transporter 1 expression and jejunal histomorphology in Eimeria challenged birds in trial 1 but negatively affected non-challenged birds in trial 1 and no effect in trial 2. Nucleotides increased bursal weights in trial 2, but not the spleen and thymus. Nucleotides effect on gastrointestinal microbiota community was independent of Eimeria, but interactive on ceca short chain fatty acid concentration and pH. Overall, nucleotides attenuated some negative effects of Eimeria but also resulted in negative effects. Supplementation of nucleotides may be most beneficial for animals encountering enteric stress conditions. en_US
dc.description.sponsorship Ontario Ministry of Agriculture, Food and Rural Affairs; McIntosh Family Professorship in Poultry Nutrition; Natural Sciences and Engineering Research Council of Canada; Canadian Bio-Systems Inc en_US
dc.language.iso en en_US
dc.rights Attribution-NoDerivs 2.5 Canada *
dc.rights.uri http://creativecommons.org/licenses/by-nd/2.5/ca/ *
dc.subject chickens en_US
dc.subject Eimeria en_US
dc.subject nucleotide en_US
dc.title THE EFFECTS OF A NUCLEOTIDE RICH YEAST SUPPLEMENT ON GROWTH PERFORMANCE, GASTROINTESTINAL ECOLOGY AND IMMUNE SYSTEM IN BROILER CHICKENS CHALLENGED WITH EIMERIA en_US
dc.type Thesis en_US
dc.degree.programme Animal and Poultry Science en_US
dc.degree.name Master of Science en_US
dc.degree.department Department of Animal Biosciences en_US
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