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Investigating a role for phospholipids in plastid pleomorphy

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dc.contributor.advisor Mathur, Jaideep
dc.contributor.author Anderson, Cole
dc.date.accessioned 2018-05-09T20:53:48Z
dc.date.available 2019-04-19T05:00:26Z
dc.date.copyright 2018-04
dc.date.created 2018-04-19
dc.date.issued 2018-05-09
dc.identifier.uri http://hdl.handle.net/10214/13039
dc.description.abstract Plastids, a defining feature of plants, produce stroma-filled extensions or tubules known as stromules. Although stromules are reliably induced upon exogenous sucrose treatment and inhibited upon silver nitrate treatment, a clear mechanism and function behind this phenomenon remains to be elucidated. The lack of inorganic phosphate appears to affect stromule levels as well as simultaneously cause a conversion of extraplastidic membrane lipids from phospholipids to galactolipids, suggesting a lipid-based mechanism for their formation. Non-specific phospholipase C 4 and non-specific phospholipase C 5, while responsible for this conversion, do not affect stromule formation. The origin of plastidial phosphatidylcholine upstream of phospholipid to galactolipid conversion is likely due to the presence of plastid associated membranes and does not play a role in stromule formation. The observations from my microscopy based studies demonstrate the organelle pleomorphy influencing ability of lysophosphatidylcholine, implicating acyl-editing, better known as the Lands cycle, in stromule formation. en_US
dc.description.sponsorship NSERC en_US
dc.language.iso en en_US
dc.subject plastid en_US
dc.subject chloroplast en_US
dc.subject PLA2 en_US
dc.subject phospholipase A2 en_US
dc.subject PC en_US
dc.subject phosphatidylcholine en_US
dc.subject LPC en_US
dc.subject lysophosphatidylcholine en_US
dc.subject LPCAT en_US
dc.subject lysophosphatidylcholine acyltransferase en_US
dc.title Investigating a role for phospholipids in plastid pleomorphy en_US
dc.type Thesis en_US
dc.degree.programme Molecular and Cellular Biology en_US
dc.degree.name Master of Science en_US
dc.degree.department Department of Molecular and Cellular Biology en_US
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