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A model of highly pathogenic avian influenza with environmental reservoir and vaccine intervention in broilers in an all-in-all-out housing system

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dc.contributor.advisor Eberl, Hermann
dc.contributor.advisor Greer, Amy
dc.contributor.author Coffey, Meagan
dc.contributor.author Eberl, Hermann
dc.contributor.author Greer, Amy
dc.date.accessioned 2018-01-05T20:56:35Z
dc.date.available 2018-01-05T20:56:35Z
dc.date.copyright 2018-01
dc.date.created 2017-12-20
dc.date.issued 2018-01-05
dc.identifier.uri http://hdl.handle.net/10214/12162
dc.description.abstract Avian influenza is a subtype of the influenza A virus which emerged as a highly infectious disease in the 1980's and has caused mass fatalities throughout the poultry industry. Domesticated birds, and specifically broilers, which are birds raised for meat consumption, can become infected and spread the pathogen rapidly due to the birds genetics and environment. Thus, the use of interventions such as biosecurity and vaccination are very important. The objective of this project was to develop an original model to study highly pathogenic avian influenza (HPAI) in broilers and to analyze the effects such as interventions of cleaning and vaccination. An SIR model was developed with the addition of an environmental reservoir to better study the spread of the influenza pathogen. The model was then extended to include the addition of an imperfect vaccine. The model and vaccination model were analyzed for stability and sensitivity of parameters. Economic values play a large role in the poultry industry and have a large influence on decision-making. An economic analysis was done to determine the monetary impact of an imperfect vaccine versus no vaccine intervention. Due to the high variability in avian influenza vaccine efficacy and their significant cost, vaccination is not always the best option financially. en_US
dc.language.iso en en_US
dc.title A model of highly pathogenic avian influenza with environmental reservoir and vaccine intervention in broilers in an all-in-all-out housing system en_US
dc.type Thesis en_US
dc.degree.programme Biophysics en_US
dc.degree.name Master of Science en_US
dc.degree.department Department of Mathematics and Statistics en_US
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