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A new bioinformatics pipeline to reveal the correlates of molecular evolutionary rates in ray-finned fishes

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dc.contributor.advisor Adamowicz, Sarah
dc.contributor.advisor Feng, Zeny May, Jacqueline 2017-10-12T13:50:05Z 2017-10-12T13:50:05Z 2017-10 2017-10-02 2017-10-12
dc.description.abstract This thesis entails a multivariable investigation of molecular rate correlates in ray-finned fishes through development of a bioinformatics pipeline. The pipeline first matches data for 32 ecological traits with evolutionary rate measurements of the mitochondrial cytochrome c oxidase subunit I (COI) barcode region for over 6000 fish species. Linear regression analyses are then performed to identify those traits that contribute most to molecular rate variation, accounting for phylogenetic non-independence. The utility of the pipeline for other researchers and the potential for further molecular rate applications are then discussed. The results indicate that biological traits such as age at maturity, longevity, and body size are more general predictors of fish COI evolution rates than environmental factors such as temperature. This thesis showcases the use of bioinformatics tools to analyze different types of biological data and emphasizes the usage of multi-parameter studies to identify the most important sources of molecular rate variation. en_US
dc.description.sponsorship This research was funded by NSERC Discovery Grants to Dr. Sarah J. Adamowicz and Dr. Zeny Feng. en_US
dc.language.iso en en_US
dc.rights Attribution-ShareAlike 2.5 Canada *
dc.rights.uri *
dc.subject Research Subject Categories en_US
dc.subject Bioinformatics en_US
dc.subject Molecular evolution en_US
dc.subject Molecular evolutionary rates en_US
dc.subject R programming language en_US
dc.subject Biodiversity en_US
dc.subject Fishes en_US
dc.subject DNA barcoding en_US
dc.title A new bioinformatics pipeline to reveal the correlates of molecular evolutionary rates in ray-finned fishes en_US
dc.type Thesis en_US Bioinformatics en_US Master of Science en_US Department of Integrative Biology en_US
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Attribution-ShareAlike 2.5 Canada Except where otherwise noted, this item's license is described as Attribution-ShareAlike 2.5 Canada