Main content

Experimentally Evoked Central Sensitization Does Not Modulate Dynamic Postural Responses to Medial-Lateral Perturbations in Healthy Young Adults

Show simple item record

dc.contributor.advisor Srbely, John
dc.contributor.author Malkin, Alexandra
dc.date.accessioned 2017-05-09T14:26:37Z
dc.date.available 2017-05-09T14:26:37Z
dc.date.copyright 2017-05
dc.date.created 2017-05-25
dc.date.issued 2017-05-09
dc.identifier.uri http://hdl.handle.net/10214/10428
dc.description.abstract This thesis is an investigation of the neuromuscular mechanisms associated with postural modulation after experimentally-induced central sensitization during dynamic movement. Central sensitization is an important mechanism in the development and maintenance of chronic pain and there’s evidence to suggest that it has the ability to modulate muscle activity and resulting balance. Our hypothesis states that capsaicin-induced central sensitization at the C4/C5 spinal segments leads to delayed leg muscle onset and time-to-peak amplitude following platform perturbations. Participants stood on a robotic motion platform and these outcome measures were quantified using surface electromyography during platform perturbations. The findings suggest that central sensitization does not change leg muscle onset and time-to-peak amplitude during medial-lateral perturbations compared to non-sensitized controls. Although some muscles showed significance in these outcome measures, overall, the findings suggest that capsaicin-induced central sensitization does not have a significant impact on leg muscle activity required to maintain balance during medial-lateral perturbations. en_US
dc.language.iso en en_US
dc.subject Central Sensitization en_US
dc.subject Perturbation en_US
dc.subject Neuromuscular en_US
dc.title Experimentally Evoked Central Sensitization Does Not Modulate Dynamic Postural Responses to Medial-Lateral Perturbations in Healthy Young Adults en_US
dc.type Thesis en_US
dc.degree.programme Human Health and Nutritional Sciences en_US
dc.degree.name Master of Science en_US
dc.degree.department Department of Human Health and Nutritional Sciences en_US
dc.rights.license All items in the Atrium are protected by copyright with all rights reserved unless otherwise indicated.


Files in this item

Files Size Format View
Malkin_Alexandra_201705_Msc.pdf 36.42Mb PDF View/Open

This item appears in the following Collection(s)

Show simple item record