Identification of genetic markers for stress responsiveness and meat quality in Canadian Yorkshire pigs

dc.contributor.advisorLu, Ray
dc.contributor.authorLarson, Shayla
dc.date.accessioned2019-05-16T17:21:17Z
dc.date.available2019-05-16T17:21:17Z
dc.date.copyright2019
dc.date.created2019-04-09
dc.date.issued2019-05-16
dc.degree.departmentDepartment of Molecular and Cellular Biologyen_US
dc.degree.departmentCampbell Centre for the Study of Animal Welfareen_US
dc.degree.grantorUniversity of Guelphen_US
dc.degree.nameMaster of Scienceen_US
dc.degree.programmeMolecular and Cellular Biologyen_US
dc.description.abstractLuman/CREB3 is a stress gene that has recently been identified in mouse models and therefore presents a promising avenue for exploring the genetic component underlying stress-responsiveness in pigs. This thesis provides a detailed account of the genetic variation that exists naturally at the Luman gene of Canadian Yorkshire and Chinese Meishan breeding pigs. We present evidence that genetic variation in the swine Luman gene is associated with individual differences in behavioural coping styles for stress, physiological stress levels, and meat quality characteristics among pigs. Notably, two haplotypes (A1 and A2) were associated with lower activity levels and exploratory behaviours in response to novelty and human interaction as well as greater meat quality, whereas haplotypes B1 and B2 were associated with the opposite characteristics. We postulate that genetic variations in the swine Luman gene may be used as markers for robustness and meat quality in pigs for animal breeding purposes.en_US
dc.description.sponsorshipAlliance Genetics Canada
dc.description.sponsorshipOntario Ministry of Agriculture, Food and Rural Affairs
dc.description.sponsorshipNatural Sciences and Engineering Research Council of Canada
dc.description.sponsorshipCFREF
dc.description.sponsorshipSwine Innovation Porc
dc.description.sponsorshipCanadian Centre for Swine Improvement
dc.identifier.urihttp://hdl.handle.net/10214/16129
dc.language.isoenen_US
dc.publisherUniversity of Guelphen_US
dc.rights.licenseAll items in the Atrium are protected by copyright with all rights reserved unless otherwise indicated.
dc.subjectgenetic markeren_US
dc.subjectstressen_US
dc.subjectmeat qualityen_US
dc.subjectpigsen_US
dc.subjectSNPen_US
dc.subjectLumanen_US
dc.subjectCREB3en_US
dc.subjecthaplotypeen_US
dc.subjectYorkshireen_US
dc.subjectMeishanen_US
dc.subjectgenetic variationen_US
dc.titleIdentification of genetic markers for stress responsiveness and meat quality in Canadian Yorkshire pigsen_US
dc.typeThesisen_US

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