Cognitive Inhibition Modifies the Affective and Incentive Value of Motivationally Salient Stimuli

dc.contributor.advisorFenske, Mark
dc.contributor.authorFerrey, Anne
dc.date.accessioned2012-07-03T17:33:14Z
dc.date.available2012-07-03T17:33:14Z
dc.date.copyright2012
dc.date.created2012-06-22
dc.date.issued2012-07-03
dc.degree.departmentDepartment of Psychologyen_US
dc.degree.grantorUniversity of Guelphen_US
dc.degree.nameDoctor of Philosophyen_US
dc.degree.programmePsychologyen_US
dc.description.abstractPeople with substance dependence show maladaptive approach responses toward stimuli related to their drug of addiction. Reducing the motivational salience of these appealing but maladaptive stimuli could decrease these inappropriate approach responses. Tasks that involve response inhibition influence the affective valence of stimuli, such that previously inhibited items are disliked compared to never-inhibited items. It is not clear, however, whether this effect can be harnessed to develop interventions to decrease the maladaptive motivational salience of addiction-related stimuli. To lay the groundwork for such an intervention, I first determined that people in treatment for substance dependence showed affective devaluation of previously-inhibited stimuli (Experiment 1). Because adolescence is associated with high risk of illegal substance use, I then examined the magnitude of the inhibitory devaluation effect in a group of adolescents from an adverse background (Experiment 2). Devaluation of inhibited stimuli increased significantly with age, suggesting that the effect occurs more strongly as the brain matures. Drug-related stimuli are extremely motivationally salient to people with substance dependence. Experiments 3-6 examined the affective consequences of inhibition for different types of motivationally salient stimuli: geometric images associated with monetary gains or losses, or sexually-appealing images. Finally, I determined that inhibition affects not only a stimulus’ affective valence, but also its motivational value. Heterosexual male participants who inhibited images of attractive females were later less likely to press a key in order to see more images of that type than participants who did not inhibit these images (Experiment 7). Taken together, this evidence suggests that computer-based tasks involving inhibition may be useful for decreasing the affective and motivational salience of drug-related stimuli in substance-dependent individuals.en_US
dc.identifier.urihttp://hdl.handle.net/10214/3764
dc.language.isoenen_US
dc.publisherUniversity of Guelphen_US
dc.rightsAttribution-NonCommercial-NoDerivs 2.5 Canada*
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/2.5/ca/*
dc.subjectMotivationen_US
dc.subjectdevaluationen_US
dc.subjectemotionen_US
dc.subjectsubstance dependenceen_US
dc.subjectadolescenceen_US
dc.titleCognitive Inhibition Modifies the Affective and Incentive Value of Motivationally Salient Stimulien_US
dc.typeThesisen_US

Files

Original bundle
Now showing 1 - 1 of 1
Loading...
Thumbnail Image
Name:
Ferrey_Anne_2012_PhD.pdf
Size:
1.71 MB
Format:
Adobe Portable Document Format
Description:
Anne E. Ferrey Ph.D. Dissertation
License bundle
Now showing 1 - 1 of 1
No Thumbnail Available
Name:
license.txt
Size:
317 B
Format:
Item-specific license agreed upon to submission
Description: