Capsule endoscopy (CE), in which an encapsulated camera is ingested, is used in human medicine to image the small intestine (SI) to aid in the diagnosis of intestinal disorders by detecting lesions, inflammation, bleeding, and tumors. The broad objective of this study was to assess the value of using the MiroCam capsule endoscope in horses. Duration of recording and image quality were assessed in two healthy Standardbred horses that each underwent four CE examinations. Good quality video segments were obtained, demonstrating SI features including distinct villi, mucosal lesions and luminal parasites. However, image transmission was intermittent and of short duration (0.5 to 82.41 minutes) and images were frequently obstructed by residual feed particles. This pilot study demonstrates the potential utility of CE to aid in diagnosis of SI conditions, however further research into signal transmission and equine fasting protocols is required before CE can be effectively used in equine medicine.