Antimicrobial resistance in Escherichia coli, Klebsiella spp., and Staphylococcus aureus isolates from bovine mastitis in Canada

dc.contributor.advisorBoerlin, P.
dc.contributor.authorNilsson, Stina
dc.date.accessioned2020-12-04T15:03:56Z
dc.date.available2020-12-04T15:03:56Z
dc.date.copyright2011
dc.degree.departmentDepartment of Pathobiologyen_US
dc.degree.grantorUniversity of Guelphen_US
dc.degree.nameMaster of Scienceen_US
dc.description.abstractThis study characterized the antimicrobial resistance (AMR) genes present in a collection of 'Escherichia coli, Klebsiella' spp., and ' Staphylococcus aureus' isolates from bovine mastitis cases in Canada. Ampicillin-resistant 'E. coli' isolates along with second-generation cephalosporin resistant 'Klebsiella' spp., any MRSA, and a collection of penicillin-resistant 'S. aureus' isolates were screened for the presence of AMR genes and, in the case of 'S. aureus ', also virulence genes. A high diversity of [beta]-lactamase genes was detected in 'E. coli' and 'Klebsiella' spp. mastitis isolates in comparison to those found in beef cattle fecal isolates by other researchers, and the ubiquitous 'bla'CMY-2 gene was found in bacteria from mastitis. The [beta]-lactam-resistant ' S. aureus' isolates contained many 'blaZ' gene variants. The first MRSA isolate from bovine mastitis in Canada was identified as ST8, a sequence type normally associated with humans.en_US
dc.identifier.urihttps://hdl.handle.net/10214/22415
dc.language.isoen
dc.publisherUniversity of Guelphen_US
dc.rights.licenseAll items in the Atrium are protected by copyright with all rights reserved unless otherwise indicated.
dc.subjectEscherichia colien_US
dc.subjectantimicrobial resistanceen_US
dc.subjectKlebsiella sppen_US
dc.subjectStaphylococcus aureusen_US
dc.subjectbovine mastitisen_US
dc.titleAntimicrobial resistance in Escherichia coli, Klebsiella spp., and Staphylococcus aureus isolates from bovine mastitis in Canadaen_US
dc.typeThesisen_US

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