A Systematic Review, Meta-Analysis and Meta-Regression of the Proportion of Campylobacter, Non- typhoidal Salmonella and E. coli O157 Cases that Develop Chronic Sequelae

Keithlin, Jessica
Journal Title
Journal ISSN
Volume Title
University of Guelph

Understanding of chronic sequelae development after infection with foodborne pathogens is limited and an increased understanding could assist with the development of more accurate burden of disease estimates. The purpose of this thesis was to determine via systematic review and meta-analysis of the published international literature, the proportion of cases of Salmonella, Campylobacter and E. coli O157 that will develop the chronic sequelae of reactive arthritis, haemolytic uraemic syndrome, irritable bowel syndrome, inflammatory bowel disease or Guillain Barré syndrome. This information can be used to increase our understanding of the relationship between infection and the development of long term health complications while providing a key piece of information for the development of accurate burden of disease estimates.

foodborne disease, non-typhoidal salmonella, E. coli O157, E. coli, Campylobacter, Salmonella, HUS, Reactive Arthritis, IBS, Irritable Bowel Syndrome, IBD, Inflammatory Bowel Disease, Guillain Barre Syndrome, GBS, chronic sequelae, sequelae, systematic review, meta-analysis, meta-regression