A nutraceutical for osteoarthritis: results of a 3-month study to determine absence of in vivo toxicity in horses

dc.contributor.advisorLindinger, M.I.
dc.contributor.authorChauhan, Nita
dc.date.accessioned2020-08-24T15:49:46Z
dc.date.available2020-08-24T15:49:46Z
dc.date.copyright2007
dc.degree.departmentDepartment of Human Biology and Nutritional Sciencesen_US
dc.degree.grantorUniversity of Guelphen_US
dc.degree.nameMaster of Scienceen_US
dc.description.abstractOsteoarthritis (OA), or degenerative joint disease is a major cause of lameness in horses. Current treatments for OA are not adequate for long term treatment. Sasha's Equine is a nutraceutical composed of shark cartilage, New Zealand green-lipped mussel, abalone and 'Biota orientalis' seed oil. The present study was aimed at determining the safety of Sasha's Equine in horses at 1x, 3x and 5x the recommended dose for 3 months. Horses' body mass (BM), resting temperature, pulse and respiratory rate (TPR), haematology, blood biochemistry, and manure production monitored throughout the study. Supplementation with Sasha's Equine at 1x, 3x and 5x the recommended dose did not significantly affect BM, TPR, urine biochemistry or manure production. There were also no clinically significant changes in haematology or blood biochemistry at these doses. We therefore concluded that Sasha's Equine is safe when consumed at up to 5x the recommended dose for 3 months in horses.en_US
dc.identifier.urihttps://hdl.handle.net/10214/20288
dc.language.isoen
dc.publisherUniversity of Guelphen_US
dc.rights.licenseAll items in the Atrium are protected by copyright with all rights reserved unless otherwise indicated.
dc.subjectOsteoarthritisen_US
dc.subjecthorseen_US
dc.subjecttreatmenten_US
dc.subjectSasha's Equineen_US
dc.subjectbody massen_US
dc.subjectresting temperatureen_US
dc.subjectpulseen_US
dc.subjectrespiratory rateen_US
dc.subjecthaematologyen_US
dc.subjectblood biochemistryen_US
dc.subjectmanure productionen_US
dc.titleA nutraceutical for osteoarthritis: results of a 3-month study to determine absence of in vivo toxicity in horsesen_US
dc.typeThesisen_US

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