Holstein bull fertility linked to more copies of a testis-specific protein in the genome

Date
2013-04-19
Authors
Hamilton, C.K.
Verduzco-Gomez, A.R.
Favetta, L.A.
Blondin, P.
King, W.A.
Institute for Community Engaged Scholarship
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Abstract

In Holstein bulls, higher fertility was linked to having more copies of TSPY (testis-specific protein found on the Y chromosome) in the genome. Bulls with more TSPY copies showed decreased TSPY gene activity and no change in semen characteristics, however, suggesting that copy number indirectly affects fertility.

Description
This summary is a project of the Institute for Community Engaged Scholarship (ICES) at the University of Guelph, with project partners: the Catalyst Centre, SPARK Program at the University of Guelph, and Knowledge Mobilization Unit at York University. This project is part of the Pan-Canadian Research Impact Network. http://csahs.uoguelph.ca/pps/Clear_Research
Keywords
cows, dairy bulls, field fertility, semen, copy number variation, testis-specific protein y-encoded
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