Exploring different components of disease transmission for Verocytotoxigenic Escherichia coli (VTEC) infections in Ontario, Canada

dc.contributor.advisorGreer, Amy
dc.contributor.authorHovdey, Roksolana
dc.date.accessioned2019-12-02T15:52:37Z
dc.date.available2019-12-02T15:52:37Z
dc.date.copyright2019-11
dc.date.created2019-11-07
dc.date.issued2019-12-02
dc.degree.departmentDepartment of Population Medicineen_US
dc.degree.grantorUniversity of Guelphen_US
dc.degree.nameMaster of Scienceen_US
dc.degree.programmePopulation Medicineen_US
dc.description.abstractThe transmission dynamics of human verocytotoxigenic Escherichia coli (VTEC) infections are not well understood. This thesis examines the transmission of VTEC, exploring the role of environmental conditions on the risk of primary infections, and the impact of person to person transmission during outbreaks. The first study explored the effect of environmental factors on VTEC infections in Ontario using case-crossover analyses. While the magnitude and direction of the effect was variable between health units, the findings demonstrate that infections were associated with hydrological conditions. The second study focused on the potential impact of person to person transmission using a mathematical model to describe an outbreak in Ontario. Based on the model results, including public health interventions targeting person-to-person transmission reduced the outbreak size by ~16%. The results from these studies demonstrate that watershed hydrology may be associated with VTEC infections, and that person to person transmission is an important transmission route to target for interventions during outbreaks.en_US
dc.identifier.urihttp://hdl.handle.net/10214/17617
dc.language.isoenen_US
dc.publisherUniversity of Guelphen_US
dc.rightsAttribution-NonCommercial-NoDerivatives 4.0 International*
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/4.0/*
dc.subjectepidemiologyen_US
dc.subjectPopulation Medicineen_US
dc.subjectEscherichia colien_US
dc.subjectmathematical modellingen_US
dc.subjectOntarioen_US
dc.subjectVTECen_US
dc.titleExploring different components of disease transmission for Verocytotoxigenic Escherichia coli (VTEC) infections in Ontario, Canadaen_US
dc.typeThesisen_US

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