The research objective was to investigate mitigation measures for reduction of energy use, emissions, and costs, for a residential house in current and future climates in Vancouver and Toronto, representing climate zones 4 and 5, respectively. The mitigation strategies investigated were: increasing vegetation, increasing thermal resistance, decreasing infiltration/exfiltration, adding a cool roof, and adding photovoltaic panels. Energy consumption simulations were conducted using the Vertical City Weather Generator (VCWG) software. Future climate data was obtained form CanRCM4 files under Representative Concentration Pathway (RCP) 4.5 and 8.5 [W m^{-2}] . The largest cost and CO_2e savings in Vancouver and Toronto came from the reduction in infiltration/exfiltration. The economic analysis showed that cost savings for mitigation efforts are dependent on individual costs in each city. Electricity prices in Vancouver were cheap, which made the use of PV systems too expensive. However, in Toronto the high price of electricity made PV systems cost effective.