The Effects of a Novel Bacillus subtilis DFM (BS-9) on Growth Performance, Indices of Intestinal Health, and Cecal Microbial Composition in Broiler Chickens Challenged with Eimeria

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dc.contributor.advisorKiarie, Elijah
dc.contributor.authorGelinas, Alison
dc.date.accessioned2023-05-18T14:20:57Z
dc.date.copyright2023-05
dc.date.created2020-04-27
dc.degree.departmentDepartment of Animal Biosciencesen_US
dc.degree.grantorUniversity of Guelphen
dc.degree.nameMaster of Scienceen_US
dc.degree.programmeAnimal Biosciencesen_US
dc.description.abstractProbiotics or direct-fed microbials (DFM) are alternatives to antibiotic growth promoters (AGP) in poultry production. However, there is limited information on their role in birds subjected to an enteric pathogen challenge. Herein are the investigations of Bacillus subtilis (BS-9) DFM on the growth performance and intestinal histomorphology (Chapter 3; Experiment 1) and on cecal microflora activity (Chapter 4; Experiment 1 & 2) in Ross x Ross 708 broiler chickens subjected to an Eimeria challenge. The DFM improved body weight, weight gain, and intestinal surface area but not feed conversion ratio (FCR). However, DFM birds had similar FCR to non-challenge control due to increased feed intake (FI), reduced members of Clostridiales, and altered SCFA production. The DFM effect on members of Firmicutes, particularly from order Clostridiales, was interactive, with the largest reduction in challenged DFM birds. Overall, DFM mitigated the adverse effects of an Eimeria challenge, suggesting potential for modulating the gut microbiota.en_US
dc.description.embargo2024-04-28
dc.description.sponsorshipNatural Sciences and Engineering Research Council of Canada - Discovery program
dc.description.sponsorshipOntario Agri-Food Innovation Alliance
dc.description.sponsorshipAAFC-CPRC Poultry Science cluster III
dc.identifier.urihttps://hdl.handle.net/10214/27627
dc.language.isoenen_US
dc.publisherUniversity of Guelphen
dc.rightsAttribution 4.0 International*
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/*
dc.subjectBroiler chickenen_US
dc.subjectBacillus subtilisen_US
dc.subjectEimeriaen_US
dc.subjectGrowth performanceen_US
dc.subjectMicrobial compositionen_US
dc.subjectIntestinal healthen_US
dc.subjectDirect-fed Microbialen_US
dc.titleThe Effects of a Novel Bacillus subtilis DFM (BS-9) on Growth Performance, Indices of Intestinal Health, and Cecal Microbial Composition in Broiler Chickens Challenged with Eimeriaen_US
dc.typeThesisen
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