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Risk factors for the use of macrolide and fluoroquinolone antimicrobials by human populations in Canada 2000-2006

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Title: Risk factors for the use of macrolide and fluoroquinolone antimicrobials by human populations in Canada 2000-2006
Author: Glass, Shiona K
Department: Population Medicine
Program: Population Medicine
Abstract: Multivariable linear and negative binomial models were produced to assess relationships among socioeconomic and influenza rate data with the use of macrolide and fluoroquinolone antimicrobials by Canadians. Varying results were found both among and between the macrolide and fluoroquinolone groups; however, a pattern of accessibility to care was apparent. Cheaper antimicrobials were used most often in the most disadvantaged populations, and more expensive antimicrobials were used most frequently in advantaged populations. Significant interactions were found between influenza and socioeconomic variables relating to unemployment, education, and degree of poverty in a population. Results suggest that antimicrobials are being prescribed and consumed at inappropriate rates in both disadvantaged and affluent populations in Canada. In order to reduce antimicrobial use and the further development of antimicrobial resistance in Canada, we suggest that responsible antimicrobial stewardship be practiced and promoted by all physicians in community and hospital settings, particularly during the influenza season.
URI: http://hdl.handle.net/10214/1997
Date: 2009-08-27


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