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Could the Genetics of Taste Affect Your Health? Lessons Learned from the Guelph Family Health Study

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Title: Could the Genetics of Taste Affect Your Health? Lessons Learned from the Guelph Family Health Study
Author: Chamoun, Elie; Mutch, David; Haines, Jess; Ma, David
Abstract: Increased consumption of energy-dense foods in modern society has led to widespread metabolic complications in children and adults. An emerging factor that may influence adverse eating behaviours is taste perception. Genetic variation in taste receptor genes may alter individual taste perception and dietary choices. Investigating taste receptors which elicit fat, sweet, and bitter taste is of particular interest as food intake patterns associated with these taste modalities are most often linked to poor health. The aim of this study was to examine associations between single nucleotide polymorphisms in the taste receptors CD36 (fat taste), T1R2 (sweet taste), and T2R38 (bitter taste) and blood biomarkers of lipid and glucose metabolism among young children (aged 1.5-5 years) in the Guelph Family Health Study. The Guelph Family Health Study is a longitudinal cohort study of families with young children. DNA was extracted from saliva and genotyped by RT-PCR. Children provided fasted blood samples and anthropometric measurements. Genotype and matched blood data from a total of 16 children were obtained in this pilot study. Results show that major allele homozygotes of the CD36 SNP had higher triglyceride levels (1.03±0.44 mmol/L) than minor allele homozygotes (0.62±0.32 mmol/L). Fasting insulin levels were also higher in major allele homozygotes (19±14 pmol/L) than minor allele homozygotes (6±2 pmol/L). These outcomes suggest an excess consumption of fatty foods which may lead to chronic metabolic pathologies.
Description: Poster was part of 'What We Know' display, held on March 1, 2017 at the Quebec Street Mall in Downtown Guelph. At 'What We Know,' the Community Engaged Scholarship Institute brought together 50 posters featuring diverse research on Guelph and Wellington from community organizations, municipal staff, faculty and students. Topics included feral cats, farmland loss, food waste, the wellbeing of children and more - all specific to Guelph and Wellington.
Date: 2017-03-01
Rights: Attribution-ShareAlike 2.5 Canada

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Attribution-ShareAlike 2.5 Canada Except where otherwise noted, this item's license is described as Attribution-ShareAlike 2.5 Canada